Table IV: Solubility of lactose.

 

Solvent Solubility at 208C unless otherwise stated

 

Lactochem Coarse Powder 0.71 0.95 —    

Lactochem Regular Powder 0.62 0.92 — Chloroform Practically insoluble    

Lactochem Powder 0.64 0.89 — Ethanol Practically insoluble    

Lactochem Fine Powder 0.61 0.84 — Ether Practically insoluble    

Lactochem Extra Fine 0.45 0.74 — Water 1 in 5.24    

Powder 1 in 3.05 at 408C    

Lactochem Super Fine 0.47 0.74 — 1 in 2.30 at 508C    

Powder 1 in 1.71 at 608C    

DMV International 1 in 0.96 at 808C    

Pharmatose DCL 15 0.50 0.64 4.8    

Pharmatose 50M 0.71 0.83 5.2    

Pharmatose 80M 0.76 0.91 5.2 11 Stability and Storage Conditions

Pharmatose 90M 0.74 0.89 5.2    

Pharmatose 100M 0.73 0.88 5.2 Mold growth may occur under humid conditions (80% relative    

Pharmatose 110M 0.73 0.89 5.2 humidity and above). Lactose may develop a brown coloration    

Pharmatose 125M 0.67 0.86 5.2 on storage, the reaction being accelerated by warm, damp    

Pharmatose 150M 0.60 0.88 5.2 conditions; see Section 12. The purities of different lactoses can    

Pharmatose 200M 0.56 0.84 5.2 vary and color evaluation may be important, particularly if    

Pharmatose 350M 0.51 0.80 5.2 white tablets are being formulated. The color stabilities of    

Pharmatose 450M 0.48 0.75 5.2 various lactoses also differ.    

HMS Coarse Powder 0.77 0.95 5.2 Solutions show mutorotation; see Section 10.    

HMS Extrafine Crystal 0.75 0.90 5.2 Lactose should be stored in a well-closed container in a cool,    

HMS Regular Grade Fine 0.64 0.89 5.2 dry place.  

Powder

HMS Impalpable 0.58 0.85 5.2

Foremost Farms USA

NF Lactose 310 0.66 0.92 4.8–5.2

NF Lactose 312 0.53 0.81 4.8–5.2

NF Lactose 313 0.44 0.72 4.8–5.2

Meggle GmbH

CapsuLac 60 0.59 0.70 5.2

GranuLac 70 0.72 0.90 5.2

GranuLac 140 0.66 0.89 5.2

GranuLac 200 0.54 0.80 5.2

GranuLac 230 0.47 0.76 5.2

PrismaLac 40 0.47 0.54 5.2

SacheLac 80 0.60 0.71 5.2